Ranking of Harmful Industries
Below is a single, cross-sector ranking of the 16 most harmful (i.e., net-negative) industries/sectors today, blending the strongest like-for-like metrics we can get across domains: deaths/DALYs, economic costs, scale of exploitation/rights abuse, and environmental externalities. Where figures are uncertain (e.g., criminal markets), I cite the most authoritative ranges and call out caveats.
Quick note on scope: "Industries" below also includes large, persistent criminal economies (e.g., trafficking, cybercrime) when they function like industries.
Top 16 most harmful industries
1 = most harmful
1. Tobacco
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Primary harm: massive premature mortality & morbidity from NCDs; second-hand smoke.
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Magnitude: >7--8+ million deaths/year globally. World Health Organization+1
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Why #1: the most consistently measured behavior-linked killer with large DALYs across all regions.
2. Alcohol
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Primary harm: injuries (crashes, violence), cancers, liver disease; social costs.
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Magnitude: ~2.6 million deaths/year (2019 baseline), ~4.7% of all deaths; country studies put social/economic costs ~2--3% GDP. World Health Organization+1
3.Fossil Fuels
Energy / air-pollution--intensive production
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Primary harm: ambient + household air pollution (cardiovascular, respiratory, cancers); climate.
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Magnitude: ~8.1 million deaths in 2021 attributable to air pollution (not all fossil---but heavily driven by it). State of Global Air
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Why not #1: avoids double-counting household biomass; still, the public-health burden is extraordinary.
4. Ultra-processed Foods
unhealthy diet industry (incl. sugary beverages)**
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Primary harm: diet-related NCDs (CVD, diabetes, some cancers).
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Magnitude: ~11 million deaths (2017) attributable to dietary risks (UPFs are a major driver within this risk family). PubMed+1
5. Illicit drugs
non-medical drug trade
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Primary harm: overdoses, blood-borne infections, violence, crime; very high DALYs.
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Magnitude: WHO: ~0.6 million deaths/year attributed to drug use (2019); GBD/UNODC show comparable order of magnitude. World Health Organization+1
6. Sex trafficking
Forced commercial sexual exploitation (part of modern slavery)**
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Primary harm: extreme, chronic rights abuse and trauma.
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Magnitude: 50 million in modern slavery (any given day, 2021), 6.3 million in forced commercial sexual exploitation; ~US$236 billion/yr in illegal profits. International Labour Organization+1
7. Arms Trade
organized violent conflict ecosystem
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Primary harm: battle and civilian deaths, displacement, destroyed health systems.
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Magnitude: ~122,500 battle-related deaths in 2023 (UCDP); world military spend = US$2.44T (2023) → US$2.72T (2024) shows scale of the sector. SAGE Journals+2SIPRI+2
8. Cybercrime
Hackers & ransomware
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Primary harm: large financial losses, critical-infrastructure disruption, spillover safety risks (e.g., hospital outages).
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Magnitude: US$16.6 billion reported losses (U.S., 2024); global estimates put total cybercrime at ~US$10.5T/yr by 2025 (methodologically broad but widely cited). Internet Crime Complaint Center+2Federal Bureau of Investigation+2
9. Healthcare Fraud
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Primary harm: diverted medical resources, delayed/denied care, patient safety risks, financial burden on healthcare systems.
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Magnitude: US$68--230 billion/yr in the U.S. alone (National Health Care Anti-Fraud Association estimates); 3--10% of total healthcare spending globally; patient harm through unnecessary procedures and delayed legitimate care.
10. Human smuggling
Distinct from trafficking
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Primary harm: deaths during irregular journeys; exploitation and extortion.
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Magnitude: ~8,938 migrant deaths in 2024 (record); smuggling market ~US$5.5--7B/yr on key routes (2016 est.). International Organization for Migration+1
11. Gambling Industry
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Primary harm: addiction, suicidality, family breakdown, crime; concentrated harms.
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Magnitude: ~1.2% of adults meet gambling-disorder criteria worldwide; England: £1.05--£1.77 bn/yr social cost; Australia: multi-billion annual social costs. World Health Organization+2GOV.UK+2
12. Industrial livestock
factory farming
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Primary harm: climate (methane), land-use change; antimicrobial resistance risks; severe animal-welfare harms.
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Magnitude: ~14.5% of anthropogenic GHG from livestock supply chains (FAO baseline; newer analyses range ~12--20%). FAOHome+1
13. Deforestation and Illegal Logging
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Primary harm: biodiversity loss, carbon emissions, Indigenous rights violations.
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Magnitude: FAO indicates ~10 Mha/yr deforestation (2015--2020); more recent assessments show continued high loss/degradation. FAOHome+1
14. Fast Fashion
resource-intensive textile industry**
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Primary harm: high GHG, water use/pollution, waste, labor abuses.
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Magnitude: fashion/textiles responsible for ~2--8% of global CO₂e; ~20% of industrial wastewater (estimates vary by method). UNEP - UN Environment Programme+1
15. Crypto Industry
as a whole: bitcoin mining + on-chain ecosystem Blockchain
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Primary harm: energy/CO₂ (primarily Bitcoin PoW), e-waste; sizable fraud/hacks externalities.
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Magnitude: Bitcoin electricity consumption tracked by Cambridge CBECI; Ethereum's merge cut emissions by ~99.9% to the kt-scale; illicit crypto flows ≈ US$40.9B (2024) (lower-bound). ccaf.io+2Chainalysis+2
16. Pornography
(legal/adult)
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Primary harm (to a subset): problematic use linked to mental-health/relationship issues; broader population-level harm metrics are limited/contested.
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Magnitude: research finds PPU (problematic pornography use) in single-digit to low-double-digit % of users in some samples; no robust global mortality/economic-cost totals. PMC+1
A few framing notes
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Apples vs. oranges: A perfect cross-domain ruler doesn't exist. I prioritized mortality/DALYs (where available), then economic costs and documented rights abuses; environmental externalities were weighted by scale and persistence.
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Regional variation: Some harms (e.g., gambling, cybercrime) have rich national cost studies but thin global syntheses; rankings could shift under different weights (e.g., climate-only, U.S.-only).
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Intersections: Several sectors amplify others (e.g., cybercrime ↔ crypto, deforestation ↔ livestock/feed, fossil fuels ↔ air pollution). I kept them distinct to show relative scale.
Working references (load-bearing sources)
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Tobacco: WHO fact sheet; OWID synthesis. World Health Organization+1
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Alcohol: WHO 2024 fact sheet & news release (2.6M deaths). World Health Organization+1
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Air pollution / fossil fuels: State of Global Air 2024 global deaths; WHO HAP fact sheet. State of Global Air+1
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Dietary risks / UPFs: GBD/Lancet 2019; PubMed abstract. The Lancet+1
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Illicit drugs: WHO 2024 release; UNODC World Drug Report portal. World Health Organization+1
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Sex trafficking / modern slavery: ILO 2022 global estimates; ILO 2024 profits update. International Labour Organization+1
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Armed conflict / arms ecosystem: UCDP 2023 battle deaths; SIPRI 2023--2024 military spending. SAGE Journals+2SIPRI+2
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Cybercrime: FBI IC3 2024 report (US$16.6B losses); global US$10.5T estimate (contextual). Internet Crime Complaint Center+2Federal Bureau of Investigation+2
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Human smuggling: IOM Missing Migrants 2024 record fatalities; UNODC market size (key routes). International Organization for Migration+1
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Gambling: WHO 2024 fact sheet; England cost study; Australia Productivity Commission echoes. World Health Organization+2GOV.UK+2
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Industrial livestock: FAO 14.5% GHG reference; range discussion. FAOHome+1
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Deforestation: FAO FRA 2020 (10 Mha/yr); 2024 degradation assessment. FAOHome+1
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Fast fashion: UNEP/UNFCCC/EU Parliament briefs (2--8% emissions; ~20% wastewater). UNEP - UN Environment Programme+1
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Crypto: Cambridge CBECI/CBNSI; Chainalysis 2025 (2024 flows); Ethereum post-merge emissions. ccaf.io+2Chainalysis+2
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Pornography (legal): Recent scholarly reviews on PPU & mental-health associations. PMC+1