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Genetic Background Effects Visualization

Open Genetic Background Effects Visualization Fullscreen

About This MicroSim

Chapter 3: Epistasis, Complementation, and Modified Ratios

Library: p5.js

Type: Interactive simulation sim-id: genetic-background-effects
Library: p5.js
Status: Specified

An interactive visualization showing how the same primary mutation produces different phenotypic outcomes in different genetic backgrounds. The user selects a primary mutation from a dropdown, then adjusts sliders representing 3 modifier genes (each with enhancer/neutral/suppressor settings). The resulting phenotype is displayed as a severity meter. The simulation demonstrates that identical primary mutations can range from mild to severe depending on modifier gene configuration. A "randomize backgrounds" button shows how variable the outcomes can be.