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Synthetic Lethality

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About This MicroSim

Chapter 13: Experimental Genetics and Model Organisms

Library: p5.js

Type: concept diagram sim-id: synthetic-lethality
Library: p5.js
Status: Specified

An interactive diagram showing the concept of synthetic lethality. Display a 2x2 grid representing combinations of wild-type and mutant alleles for Gene A and Gene B. Three quadrants (WT/WT, mut/WT, WT/mut) show viable cells (green). The fourth quadrant (mut/mut) shows cell death (red with X). Include toggles to show the parallel pathway model: when either pathway functions, the cell survives; when both are disrupted, the cell dies.