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CRISPR-Cas9 Repair Pathways

Open CRISPR-Cas9 Repair Pathways Fullscreen

About This MicroSim

Chapter 13: Experimental Genetics and Model Organisms

Library: Mermaid

Type: flowchart sim-id: crispr-repair-pathways
Library: Mermaid
Status: Specified

A flowchart showing the two repair pathways after CRISPR-Cas9 creates a double-strand break. Left branch: NHEJ pathway leading to random indels and gene disruption. Right branch: HDR pathway using a donor template leading to precise edits (point mutations, insertions, or gene replacements). Include decision point about whether a repair template is provided.